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Table 3 Main clinical characteristics of included articles

From: Subcutaneous immunotherapy with depigmented-polymerized allergen extracts: a systematic review and meta-analysis

No.

Year

First autor

Rhinoconjunctivitis severity (ARIA)

Asthma severity (GINA)

Mean age (SD or range)

PDCO groups of age

Patients not included in PP analysis

Active group (%)

Placebo group (%)

1

2010

Pfaar

Mild to severe

Only intermittent

39 (18 to 65)

Only adults

14.6

14.9

2

2013

Pfaar

Moderate to severe

Only intermittent

31 (12.4)

Adolescent included

14.5

17.2

3

2012

Pfaar

Moderate to severe

Only intermittent

33 (11 to 69)

Children Included

23.7

25

4

2010

Höiby 

Mild to severe

Intermittent to mild

33 (7 to 69)

Children Included

22.6

30

5

2006

Colás

Mild to severe

Intermittent to mild

34 (18 to 51)

Only adults

5

5

6

2005

Ameal

Mild to severe

Intermittent to moderate

23 (14 to 48)

Adolescent included

9.4

16.1

7

2006

García-Robaina

Moderate to severe

Intermittent to moderate

24 (9.3)

Adolescent included

20

20

8

2005

Álvarez-Cuesta

Moderate to severe

Intermittent to mild

28 (17 to 58)

Adolescent included

  1. ARIA allergic rhinoconjunctivitis and its impact on Asthma, GINA global initiative for Asthma, PDCO European Medicines Agency. Paediatric Committee, PP Per protocol, SD Standard deviation