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Fig. 2 | Clinical and Translational Allergy

Fig. 2

From: Subcutaneous immunotherapy with depigmented-polymerized allergen extracts: a systematic review and meta-analysis

Fig. 2

AIT with DPAEs compared with placebo at the time of primary analysis in original publications. Outcome: combined symptom and medication score (cSMS) calculated with total scores from published articles. Four subgroups of asthma and rhinoconjunctivitis severity are delimited by solid and dashed lines. *Asthma classification: (0) Only intermittent asthma patients included; (1) Intermittent to mild persistent asthma patients included; (2) Intermittent to moderate persistent asthma patients included. **Rhinoconjunctivitis classification: (0) Any rhinoconjunctivitis severity included; (1) Moderate to severe rhinoconjunctivitis included. 95%CI: 95% confidence interval; m months, SD standard deviation, SMDs standardized mean difference

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