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Fig. 1 | Clinical and Translational Allergy

Fig. 1

From: Two grass pollen tablets commercially available for allergy immunotherapy display different IgE epitope repertoires

Fig. 1

Inhibition curves corresponding to one tablet of 5-grass pollen extract (plain lines and losanges) and three tablets of 1-grass pollen extract (dashed lines and plain circles). Increasing dilutions of tablets were allowed to compete with immobilized 12-grass pollen allergens for the binding of serum IgE from a grass pollen-allergic patient, and the IgE that remained bound to the immobilized allergens were detected. Patients were classified in 3 tertiles, according to the difference between the AUC obtained with the 5-grass pollen tablet and the one obtained with three 1-grass pollen tablets. Patients of the first, second and third tertiles are exemplified, respectively, by Swedish patient #00222 and Spanish patient #00111 (top), Swedish patient #00212 and Spanish patient #00108 (middle), and Swedish patient #00202 and Spanish patient #00118 (bottom)

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