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Table 1 The ICT solution

From: Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma

App (MASK-air) deployed in 23 countries: TRL9 (Technology Readiness level), Electronic clinical decision support system (ARIA e-CDSS): TRL 7, e-physician questionnaire deployed in 16 countries: TRL9

MASK-air good practice [1, 14]

  5-year work

  App: 26,000 users, 23 countries, 17 languages

  GDPR including geolocation [105]

  GP of the EIP on AHA, follows CHRODIS [14]

  Based on 11 EU grants (MeDALL [106], GA2LEN [107]) including—in 2018—POLLAR [4], VIGOUR, DigitalHealthEurope and Euriphi

  From a validated “research”  tool (2004-2018) to large scale deployment (2019–)

    Validation with COSMIN guidelines [40]

    Baseline characteristics [12]

    Work productivity [41, 42]

    EQ-5D [43]

    Novel phenotypes of allergic diseases [44]

    Adherence to treatment and novel approaches to inform the efficacy of treatment [45].

  Patient’s organizations and scientific societies involved

  GARD (WHO alliance)

  Presented during WHO and EU ministerial meetings

  Next-generation care pathways meeting (Dec 3, 2018) with the EIP on AHA, POLLAR (EIT Health) and GARD

  47 MASK papers in 12 languages [99, 108, 109]

  Dissemination according to the EIP on AHA [26]

Transfer of innovation (TWINNING [110])

  Interoperable platform with MASK

  25 RS plus Argentina, Australia, Brazil, Canada, Mexico [99, 108, 109]

  700 patients enrolled

  GDPR solutions being solved

ARIA e-CDSS [9, 111]

  Interoperable platform with MASK

  Based on an expert meeting

  Electronic version available

  GDPR solutions being solved

Developments

  App for home services

  App for sleep

  App for COPD

  App for other chronic diseases