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Table 1 Characterization of the three groups included in the study. Comparison of the non-atopic asthmatics (NAA) to non-atopic controls (NAC) and atopic asthmatics (AA)

From: Characterization of a subgroup of non-type 2 asthma with cow’s milk hypersensitivity in young subjects

  NAA (n = 24) NAC (n = 24) AA (n = 29) p value NAA-NAC p value NAA-AA
Females (%) 60 54.1 48.2 0.687 0.398
Age (years) 18.5 ± 5.90 19.5 ± 5.98 18.4 ± 5.80 0.526 0.946
Height (cm) 163 ± 13.6 172 ± 11.5 166 ± 14.3 0.021 0.553
Weight (kg) 59.3 ± 15.9 65.9 ± 16.2 61.6 ± 19.3 0.161 0.646
FeNO (ppb) 9.78 (8.15, 11.7) 10.5 (9.01, 12.3) 29.2 (19.4, 44.2) 0.534 < .001
B-Eos 0.118 (0.088, 0.159) 0.086 (0.067, 0.110) 0.357 (0.257, 0.498) 0.097 < .001
B-Neu 3.23 (2.68, 3.90) 3.13 (2.65, 3.70) 3.26 (2.85, 3.72) 0.796 0.941
Phadiatop 0.053 (0.041, 0.069) 0.046 (0.037, 0.057) 22.8 (12.5, 41.6) 0.349 < .001
fx5 0.054 (0.038, 0.073) 0.053 (0.038, 0.073) 2.77 (0.963, 7.98) 0.627 < .001
Total IgE 22.8 (14.1, 36.6) 15.6 (8.81, 27.7) 458 (334, 628) 0.300 < .001
S-ECP 9.76 (7.62, 12.5) 8.33 (6.02, 11.5) 20.0 (14.9, 26.9) 0.423 < .001
P-CRP 0.510 (0.267,0.973) 0.522 (0.288, 0.945) 0.551 (0.327, 0.928) 0.956 0.846
S-HNL 75.2 (63.0, 89.7) 73.4 (62.7, 86.0) 72.1 (63.6, 81.8) 0.835 0.684
Smoking (%) 0 8.33 6.89 0.146 0.187
ICS (µg) 438 (312, 615) 395 (307, 509) 0.876
LTRA (%) 24.0 20.7 0.999
ACT 18.8 ± 4.51 20.0 ± 2.89 0.140
mAQLQ 5.17 ± 1.20 5.74 ± 0.821 0.045
FEV1 (%) 92.7 ± 12.5 98.0 ± 13.5 91.1 ± 16.3 0.156 0.701
FEV1 < 80 (%) 16.0 4.17 24.1 0.178 0.468
FEV1/FVC 82.6 (79.5, 85.8) 87.7 (85.4, 90.1) 80.5 (76.8, 84.2) 0.011 0.402
PD20 (mg) 0.677 (0.297, 1.54) 4.56 (3.25, 6.41) 0.393 (0.130, 1.19) < .001 0.422
Recent asthma attacks 56.0 48.2 0.320
  1. Mean ± SD, Geometric mean (95% CI). IgE concentrations in kUA/L, white blood cells in × 109/L, P-CRP in mg/L, and S-ECP and S-HNL in µg/L