Fig. 2

Cumulative distribution function (CDF) of all instruments plotted against percentage of most severe value, and presented for food and drug challenges, respectively. Instruments are divided into the relative shift compared to the Sampson5 (black line) based on kappa statistics. Red lines indicate instruments with different distribution between food and drug challenges. ⁽⁻⁾3-step scales with best concordance (highest Kappa values) to Sampson5 recalculated as 1 + 2, 3 + 4, 5. 4-step scales with best concordance (highest Kappa values) to Sampson5 recalculated as 1 + 2, 3, 4, 5. Niggemann6 had best concordance to Sampson5 when recalculated into 1, 2, 3, 4 + 5, 6. ⁽⁰⁾3-step scales with best concordance (highest Kappa values) to Sampson5 recalculated as 1 + 2, 3, 4 + 5. ⁽⁺⁾3-step scales with best concordance (highest Kappa values) to Sampson5 recalculated as 1, 2 + 3, 4 + 5. 4-step scales with best concordance (highest Kappa values) to Sampson5 recalculated as 1, 2, 3, 4 + 5. ASCA6 had best concordance to Sampson5 as when recalculated into 5-step scale = 1 + 2, 3, 4, 5, 6. *Sampson5 unmodified