From: The kinase LRRK2 is differently expressed in chronic rhinosinusitis with and without nasal polyps
Control subjects | Patients with CRSsNP | Patients with CRSwNP | |
---|---|---|---|
No. of patients | 17 | 23 | 34 |
Sex, male/female | 12/5 | 12/11 | 20/14 |
Age (years), mean (SD) | 36 (8) | 52 (17) | 37 (13) |
Atopy, no. | 0 | 4 | 6 |
Asthma, no. | 0 | 0 | 2 |
Aspirin intolerance, no. | 0 | 0 | 0 |
Smoking, no. | 0 | 10 | 16 |
Operation history, no. | 0 | 0 | 2 |
Methodologies used | |||
Tissue IHC | 10 | 16 | 25 |
Tissue mRNA | 15 | 21 | 30 |
Tissue western blot | 9 | 9 | 9 |