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Fig. 5 | Clinical and Translational Allergy

Fig. 5

From: The efficacy of oral and subcutaneous antigen-specific immunotherapy in murine cow’s milk- and peanut allergy models

Fig. 5

Cytokine concentrations after ex vivo stimulation of splenocytes with whey or PE determined by ELISA. Splenocytes were cultured for 96 h in the presence of PE, whey or medium (medium data not shown). a, b IL-5 concentration. c, d IL-10 concentration. e, f IL-13 concentration. g, h IFNγ concentration. Data are represented as mean ± SEM n = 6/8 mice/group. Statistical analysis was performed using one-way ANOVA and Dunnett’s post hoc test for multiple comparisons. #P < 0.05; ##P < 0.01; ###P < 0.001; ####P < 0.0001 compared to sham-sensitized control. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001 compared to whey- or PE-sensitized control. PE peanut extract, OIT oral immunotherapy, SCIT subcutaneous immunotherapy, IT immunotherapy

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