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Table 1 Subjects’ characteristics

From: Exploratory analysis of CD63 and CD203c expression in basophils from hazelnut sensitized and allergic individuals

  Controls (n = 10) Sensitized (n = 20) OAS (n = 20) Systemic (n = 12) p values
Age (median [min–max] in years) 30 [20–57] 26 [19–60] 32 [21–51] 40 [24–62] NS
Male sex (%) 2 (20%) 12 (60%) 6 (30%) 2 (17%) 0.041c
Atopic history [number (%)]
 Allergic rhinitis 3a (30%) 14 (70%) 16 (75%) 9 (75%)  
 Atopic dermatitis 2 (20%) 5 (25%) 9 (50%) 5 (33%)  
 Allergic asthma 9 (35%) 10 (55%) 8 (58%)  
SPT (median [min–max] in mm)
 Birch 0* 6 [0–12] 7 [0–11] 9 [3–11] NS
 Hazelnut 0* 4 [3–8] 5 [3–10] 6 [4–14] NS
 Celery 0* 0 [0–7] 3 [0–10] 4 [0–7] NS
 Apple 0* 3 [0–8] 4 [0–7] 5 [0–20] NS
 Carrot 0* 0 [0–10] 3 [0–15] 4 [0–14] NS
IgE (median [min–max] in kU/l)
 Total-IgE 16 [3–34]* 184 [20–2097] 178 [24–6861] 59 [26–4801] NS
 sIgE Bet v 1 0.0 [0.0–0.1]* 3.5 [0.0–16.2] 10.2 [0.0–72.4] 5.9 [0.1–43.6] NS
 sIgE Cor a 1 0.0 [0.0–0.1]* 1.9 [0.0–7.4] 6.7 [0.0–63.8] 3.5 [0.1–28.1] 0.0254d
 sIgE Cor a 8 n.d. n.d. 0.2 [0.0–1.3] 0.0 [0.0–0.0] NS
Ratiob (median [min–max])
 rBet v 1/total-IgE 0.00* 0.04 [0.00–4.19] 0.07 [0.00–13.0] 0.04 [0.00–11.9] NS
 rCor a 1/total-IgE 0.00* 0.02 [0.00–0.80] 0.20 [0.00–4.36] 0.18 [0.00–4.77] 0.0226e
  1. Statistical significances were analyzed with Kruskal–Wallis test
  2. * Significant difference of the control group versus the other groups
  3. aAccording to case history, not caused by birch pollen
  4. bCalculated as sIgE * sIgE/total IgE
  5. cSensitized versus control and systemic group
  6. dSensitized versus OAS group
  7. eSensitized versus OAS and systemic group