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Table 1 Subjects’ characteristics

From: Exploratory analysis of CD63 and CD203c expression in basophils from hazelnut sensitized and allergic individuals

 

Controls (n = 10)

Sensitized (n = 20)

OAS (n = 20)

Systemic (n = 12)

p values

Age (median [min–max] in years)

30 [20–57]

26 [19–60]

32 [21–51]

40 [24–62]

NS

Male sex (%)

2 (20%)

12 (60%)

6 (30%)

2 (17%)

0.041c

Atopic history [number (%)]

 Allergic rhinitis

3a (30%)

14 (70%)

16 (75%)

9 (75%)

 

 Atopic dermatitis

2 (20%)

5 (25%)

9 (50%)

5 (33%)

 

 Allergic asthma

9 (35%)

10 (55%)

8 (58%)

 

SPT (median [min–max] in mm)

 Birch

0*

6 [0–12]

7 [0–11]

9 [3–11]

NS

 Hazelnut

0*

4 [3–8]

5 [3–10]

6 [4–14]

NS

 Celery

0*

0 [0–7]

3 [0–10]

4 [0–7]

NS

 Apple

0*

3 [0–8]

4 [0–7]

5 [0–20]

NS

 Carrot

0*

0 [0–10]

3 [0–15]

4 [0–14]

NS

IgE (median [min–max] in kU/l)

 Total-IgE

16 [3–34]*

184 [20–2097]

178 [24–6861]

59 [26–4801]

NS

 sIgE Bet v 1

0.0 [0.0–0.1]*

3.5 [0.0–16.2]

10.2 [0.0–72.4]

5.9 [0.1–43.6]

NS

 sIgE Cor a 1

0.0 [0.0–0.1]*

1.9 [0.0–7.4]

6.7 [0.0–63.8]

3.5 [0.1–28.1]

0.0254d

 sIgE Cor a 8

n.d.

n.d.

0.2 [0.0–1.3]

0.0 [0.0–0.0]

NS

Ratiob (median [min–max])

 rBet v 1/total-IgE

0.00*

0.04 [0.00–4.19]

0.07 [0.00–13.0]

0.04 [0.00–11.9]

NS

 rCor a 1/total-IgE

0.00*

0.02 [0.00–0.80]

0.20 [0.00–4.36]

0.18 [0.00–4.77]

0.0226e

  1. Statistical significances were analyzed with Kruskal–Wallis test
  2. * Significant difference of the control group versus the other groups
  3. aAccording to case history, not caused by birch pollen
  4. bCalculated as sIgE * sIgE/total IgE
  5. cSensitized versus control and systemic group
  6. dSensitized versus OAS group
  7. eSensitized versus OAS and systemic group