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Table 3 The adjusted odds ratios of atopic sensitization and atopic disease in adolescence in 617 Norwegian children by changes in weight/BMI SDS after backward stepwise selection of potential confounders (one model for each predictor variable)

From: Body mass index and physical activity in early childhood are associated with atopic sensitization, atopic dermatitis and asthma in later childhood

Predictor Outcome variable (final analyses)
Atopic sensitizationa,b Allergic rhinoconjunctivitisa Atopic dermatitisc
Age n OR 95 % CI LR-p n OR 95 % CI LR-p n OR 95 % CI LR-p
Weight SDS
Birth to 3 months 361 1.10 (0.87, 1.38) 0.408 534 0.90 (0.74, 1.09) 0.292 500 0.98 (0.80, 1.17) 0.835
BMI SDS
3–6 months 351 1.15 (0.83, 1.60) 0.413 519 0.96 (0.71, 1.30) 0.794 485 1.15 (0.85, 1.56) 0.363
6 months to 1 year 360 1.30 (0.95, 1.76) 0.100 534 1.11 (0.83, 1.48) 0.470 500 1.07 (0.81, 1.42) 0.638
1–4 years 325 0.82 (0.62, 1.09) 0.173 456 0.82 (0.63, 1.07) 0.150 427 1.46 (1.11, 1.92) 0.005
4 years to first follow-upd 315 0.99 (0.78, 1.26) 0.940 450 1.01 (0.80, 1.28) 0.917 422 0.87 (0.70, 1.09) 0.223
First to second follow-upe 349 0.96 (0.65, 1.43) 0.843 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A
  1. First follow-up: 10.8 years (girls) and 11.8 years (boys); Second follow-up: 12.8 years (both sexes)
  2. Italics numbers indicate statistically significant results
  3. n number of participants, OR odds ratio, CI confidence interval, LR-p likelihood ratio-test p-value refers to predictor only, BMI body mass index (kg/m2), SDS standard deviation score, N.A. not applicable
  4. aAdjusted for sex, weight/BMI SDS at start of interval, gestational age, preeclampsia (none/mild or moderate/severe)
  5. bn = 388. Ordinal response: none, low grade, high grade (sum of specific IgE ≥ 3.9 kU/l; above the lower quartile of all children being sensitized)
  6. cAdjusted for sex, weight/BMI SDS at start of interval, mother’s asthma and mother’s smoking
  7. dAlso adjusted for physical activity at 3–6 years
  8. eAlso adjusted for physical activity at 6–10 years