Table 2 Clinical characteristics of LTG-induced cADRs group and LTG-tolerant group
LTG-induced cADRs group (n = 16) | LTG-tolerant group (n = 50) | p value | |
|---|---|---|---|
Gender (male: female) | 6:10 | 12:38 | 0.340 |
1:2 (SJS/TEN) | 1.000 | ||
5:8 (MPE) | 0.353 | ||
Mean age (years) | 35.5 ± 21.7 | 38.2 ± 19.0 | 0.646 |
52.3 ± 24.0 (SJS/TEN) | 0.415 | ||
32.0 ± 20.9 (MPE) | 0.353 | ||
Starting dosage of LTG (mg/day) | 51.6 ± 26.6 | 77.6 ± 62.0 | 0.109 |
41.7 ± 14.4 (SJS/TEN) | 0.325 | ||
53.8 ± 28.6 (MPE) | 0.186 |