Table 11 Clinical information and functional assays results from three hypersensivity patients to antibiotics
Patient information | Lymphocyte transformation test | Change in the pattern of expresion of miRNAs with drugs | ||||||
|---|---|---|---|---|---|---|---|---|
Code | Sex | Age | Skin reaction | SI/Drug (μg/ml) | miRNA | Drug (μg/ml) | Relative expression | Time (h) |
SMX1 | F | 60 | MPE | 5.0/SMX (200) 5.2/SMX-NO (20) | 142 | SMX (400) | 153 ± 28 | 12 |
18a | SMX-NO (12) | 71.6 ± 1.21 | 24 | |||||
155 | SMX-NO (12) | 5.6 ± 1.1 | 24 | |||||
SMX2 | M | 35 | MPE | 2.0/SMX (400) 3.0/SMX-NO (20) | 18a | SMX (400) | 2.5 ± 0.6 | 24 |
21 | SMX-NO (12) | 6.3 ± 3.2 | 24 | |||||
142 | SMX (400) | 3.9 ± 0.7 | 24 | |||||
LVF1 | M | 47 | MPE | 2.0/LVF (10) | 142 | LVF (10) | 12.2 ± 0.9 | 24 |
18a | LVF (10) | 4.0 ± 0.4 | 48 | |||||
155 | LVF (10) | 5.1 ± 1.1 | 48 | |||||