Fig. 3

Clinical presentations of strontium ranelate-induced severe cutaneour adverse drug reactions. A case of Stevens–Johnson syndrome (SJS) had necrotic erosive lesions on the lips and scattered dusky red macules over the face and neck (a), and close up view of the nape and back with dusky macules/patches and some necrotic epidermal detachment (b). Another case of drug reaction with eosinophilia and systems symptom presented with facial edema (c), and extensive confluent infiltrative erythematous eruption disseminated to the truck (d)