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Table 2 Characteristics of hairdressers with a positive specific inhalation challenge

From: Optimizing diagnostic tests for persulphate-induced respiratory diseases

ID Age (y) WRAS WRRS Stop/resume test Duration of exposure before symptoms (y) Time from exposure to symptom Time since last exposure to persulphates (y) Baseline FEV1/FVC (% of pred.) MCh PD20 (µg)
2 21 + + P 5 Within hours CE 87 (103 %) 330
5 29 + + P 11 Not definable CE 86.7 (104 %) N
8 32 + + P 1.5 Within minutes 8 85.5 (103 %) 346
10 22 + + P 4–5 Within hours CE 80.6 (96 %) N
16 23 + + P 0.5–1 Within minutes 2 85.4 (101 %)
Rever: 12 %
N
19 23 + + P 0.5–1 Within minutes 1/3 94.9 (113 %) N
ID Age (y) FeNO (ppb) T-IgE (kU/L) Atopya HRT PP (mg/mL) HRT SP (mg/mL) HRT AP (mg/mL) SIC response Classification of SIC response
2 21 6.3 73.2 No N N 2.5 R
A
4 and 8 after 3rd exposure (late reaction)
5 29 6.2 8.7 Yes N 10.0 10.0 R 1 h after 3rd exposure (immediate reaction)
8 32 31.2 46.4 Yes N N 5.0 R 1 h after 3rd exposure (immediate reaction)
10 22 7.4 26.6 No N N 10.0 R
A
1 and 3 h after 3rd exposure (immediate reaction/late reaction)
16 23 13.0 39.8 Yes 10.0 2.5 1.25 R After 2nd exposure (immediate reaction)
19 23 16.9 63.6 Yes 0.63 0.63 R After 3rd exposure (immediate reaction)
  1. y years, WRAS work-related asthma symptoms, WRRS work-related rhinitis symptoms, MCh methacholine challenge, FeNO fractional exhaled nitrogen oxide (increased values in italics), T-IgE total immunoglobulin E, HRT histamine release test, PP potassium persulphate, AP ammonium persulphate, SP sodium persulphate, SIC specific inhalation challenge, N negative, P positive, CE currently exposed, R rhinitis, A asthma
  2. aDefined as ≥1 positive SPT to common inhalant allergens