Table 1 Candidate SNPs

rs2155219 ^a

G/G: 0,30

G/T: 0,43

0.15

C11orf30: Regulator, represses transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. LRRC32: Associated with allergic rhinitis and rhinitis

rs17616434 ^b

C/C: 0,06

C/T: 0,31

T/T: 0,62

0.371

TLR10: Toll Like Receptor 10. Pathogen activation, activation innate immunity. TLR1: Toll Like Receptor 1. Specifically recognizes diacylated and triacylated lipopeptide. TLR6: Toll Like Receptor 6. This receptor functionally interacts with toll-like receptor 2. associated with an increased risk of asthma in some populations. FAM114A1: May play a role in neuronal cell development

rs6586513 ^a

A/A: 0,51

A/C: 0,49

0.15

CROCC: Major structural component of the ciliary rootlet. Contributes to centrosome cohesion before mitosis. ATP13A2: ATPase Type 13A2. Transports inorganic cations and other substrates. SDHB: succinate dehydrogenase complex. Complex 2 of respiratory chain. MFAP2: Microfibrillar-associated protein. Major antigen of elastin-associated microfibrils

rs3860069 ^a

A/A: 0,50

A/C: 0,45

C/C: 0,05

0.343

TLR6: Toll Like Receptor 6. This receptor functionally interacts with toll-like receptor 2. associated with an increased risk of asthma in some populations. TLR10: Toll Like Receptor 10. Pathogen activation, activation innate immunity. TLR1: Toll Like Receptor 1. Specifically recognizes diacylated and triacylated lipopeptide. FAM114A1: May play a role in neuronal cell development

rs6898653 ^a

A/A: 0,59

A/G: 0,36

G/G: 0,05

1

SEMA6A: expression in developing neuronal tissue. Is required for proper development of the thalamocortical projection

rs2069772 ^a

A/A: 0,52

A/G: 0,38

G/G: 0,10

0.527

IL2: Interleukin 2. Secreted cytokine for proliferation of T and B lymphocytes. Produced by T cells. ADAD1: binds to RNA. Plays a role in spermatogenesis. KIAA1109: associated with celiac disease