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Table 2 WAO classification of treatment-related systemic reactions

From: An accelerated dose escalation with a grass pollen allergoid is safe and well-tolerated: a randomized open label phase II trial

  Group I accelerated Group II conventional
Reactions per number of injections
 Total number of injections 371 557
 Injections without reactions 362 (97.6 %) 553 (99.3 %)
 WAO Grade 1 5 (1.3 %) 2 (0.4 %)
 WAO Grade 2 3 (0.8 %) 2 (0.4 %)
 WAO Grade not classified 1 (0.3 %)a 0 (0.0 %)
Patients with systemic reactions
 Total number of patients 61 61
 Patients without reaction 52 (85.2 %) 57 (93.4 %)
 WAO Grade 1 5 (8.2 %) 2 (3.3 %)
 WAO Grade 2 3 (4.9 %) 2 (3.3 %)
 WAO Grade not classified 1 (1.6 %)a 0 (0.0 %)
  1. aPeak expiratory flow decrease without clinical symptoms