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Table 3 Secondary endpoints, full analysis set

From: Treatment of acute rhinitis with a nasal spray containing tramazoline and essential oils: a multicenter, uncontrolled, observational trial

  Children Adolescents Adults Total
Patients, N (%) 108 (36.0) 30 (10.0) 162 (54.0) 300 (100)
Blocked nose
 Mean score at final visit (SD) 0.2 (0.5) 0.2 (0.5) 0.2 (0.4) 0.2 (0.4)
 Mean change from first visit (SD) −2.2 (0.9) −2.2 (0.9) −2.5 (0.7) −2.4 (0.8)
 Median score at final visit (min, max) 0 (0, 2) 0 (0, 2) 0 (0, 2) 0 (0, 2)
 Median change from first visit (min, max) −2 (−3, 1) −2 (−3, 0) −2 (−3, 0) −2 (−3, 1)
Sneezing
 Mean score at final visit (SD) 0.1 (0.2) 0.1 (0.3) 0.0 (0.2) 0.0 (0.2)
 Mean change from first visit (SD) −1.4 (1.0) −1.5 (0.9) −2.0 (0.6) −1.4 (0.9)
 Median score at final visit (min, max) 0 (0, 1) 0 (0,1) 0 (0, 2) 0 (0, 2)
 Median change from first visit (min, max) −1 (−3, 0) −1 (−3, 0) −1 (−3, 2) −1 (−3, 2)
Runny nose
 Mean score at final visit (SD) 0.1 (0.3) 0.2 (0.5) 0.1 (0.4) 0.1 (0.4)
 Mean change from first visit (SD) −2.2 (0.8) −2.0 (0.8) −2.1 (0.9) −2.2 (0.8)
 Median score at final visit (min, max) 0 (0, 2) 0 (0, 2) 0 (0, 2) 0 (0, 2)
 Median change from first visit (min, max) −2 (−3, 0) −2 (−3, 0) −2 (−3, 1) −2 (−3, 1)
Improvement in daily activities
 Mean score at final visit (SD) 1.2 (0.5) 1.1 (0.3) 1.3 (0.5) 1.3 (0.5)
 Median score at final visit (min, max) 1 (1, 3) 1 (1, 2) 1 (1, 3) 1 (1, 3)
Improvement in sleep
 Mean score at final visit (SD) 1.2 (0.7) 1.3 (0.8) 1.3 (0.5) 1.3 (0.6)
 Median score at final visit (min, max) 1 (1, 4) 1 (1, 4) 1 (1, 3) 1 (1, 4)
Patients’ effectiveness assessment, N (%)
 Very good 95 (88.0) 24 (80.0) 103 (63.6) 222 (74.0)
 Good 11 (10.2) 5 (16.7) 54 (33.3) 70 (23.3)
 Fair 2 (1.9) 1 (3.3) 5 (3.1) 8 (2.7)
 Poor 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Investigators’ effectiveness assessment, N (%)
 Very good 91 (84.3) 24 (80.0) 97 (59.9) 212 (70.7)
 Good 14 (13.0) 5 (16.7) 55 (34.0) 74 (24.7)
 Fair 2 (1.9) 1 (3.3) 9 (5.6) 12 (4.0)
 Poor 1 (0.9) 0 (0.0) 0 (0.0) 1 (0.3)
 Missing 0 (0.0) 0 (0.0) 1 (0.6) 1 (0.3)