Table 1 Demographics and baseline characteristics, treated set
Children | Adolescents | Adults | Total | |
|---|---|---|---|---|
Patients, N (%) | 108 (36.0) | 30 (10.0) | 162 (54.0) | 300 (100) |
Mean age in years (SD) | 8.4 (2.0) | 14.6 (1.3) | 42.1 (15.9) | 27.2 (20.0) |
Sex, N (%) | ||||
Female | 37 (34.3) | 15 (50.0) | 94 (58.0) | 146 (48.7) |
Male | 71 (65.7) | 15 (50.0) | 68 (42.0) | 154 (51.3) |
Height (SD) | 134 (15.1) | 167 (16.9) | 173 (9.8) | 158 (22.1) |
Weight (SD) | 31.8 (10.2) | 59.6 (16.1) | 75.3 (18.2) | 58 (25.5) |
Mean days since symptom onset (SD) | 1.3 (1.2) | 1.1 (1.9) | 1.4 (1.9) | 1.3 (1.7) |
Baseline mean symptom score (SD) | 2.1 (0.6) | 2.1 (0.6) | 2.1 (0.6) | 2.1 (0.6) |
Pretreated with other medications, N (%) | 8 (7.4) | 6 (20.0) | 30 (18.5) | 44 (14.7) |
Concomitant diagnosis, N (%)a | 48 (44.4) | 8 (26.7) | 45 (27.8) | 101 (33.7) |
Ear and labyrinth disorders | 22 (20.4) | 4 (13.3) | 5 (3.1) | 31 (10.3) |
Respiratory, thoracic and mediastinal disorders | 21 (19.4) | 2 (6.7) | 3 (1.9) | 26 (8.7) |
Vascular disorders | 0 (0.0) | 0 (0.0) | 18 (11.1) | 18 (6.0) |
Gastrointestinal disorders | 4 (3.7) | 0 (0.0) | 13 (8.0) | 17 (5.7) |
Concomitant medications, N (%)b | 49 (45.4) | 7 (23.3) | 45 (27.8) | 101 (33.7) |
Antibiotics, N (%) | 31 (28.7) | 3 (10.0) | 4 (2.5) | 38 (12.7) |
Smoker, N (%) | 0 (0.0) | 0 (0.0) | 23 (14.2) | 23 (7.7) |