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Table 4 Summary of PK parameters of MT (10 mg/immediate release table) from different countries

From: Interchangeability and comparative effectiveness between generic and brand montelukast immediate release tablets after a single oral administration in healthy volunteers

Formulation

AUC0–24 mean ± SD ng h/mL

AUC0–∞ mean ± SD ng h/mL

Cmax ng/mL

t1/2 h

Generic

3251.6 ± 1221.8

3284.9 ± 1270.0

460.5 ± 170.9

3.4 ± 1.6

Brand

3162.5 ± 1537.6

3196.5 ± 1546.8

440.6 ± 227.4

3.4 ± 1.4

Generic

2443 ± 729

2530 ± 763

396 ± 120

4.9 ± 1.0

Brand

2659 ± 905

2750 ± 960

444 ± 153

4.9 ± 1.0

Generic

334.07 ± 1247.39

3.837.01 ± 1294.98

526.27 ± 178.24

3.9 ± 0.5

Brand

3733.46 ± 1248.14

3833.83 ± 1289.03

540.60 ± 190.88

4.0 ± 0.7

Generic

3707.37 ± 1 417.53

3818.73 ± 1520.90

580.40 ± 215.99

4.54 ± 0.63

Brand

3433.37 ± 1359.8

3546.19 ± 1447.11

543.13 ± 222.17

4.72 ± 0.77