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Fig. 2 | Clinical and Translational Allergy

Fig. 2

From: Use of a basophil activation test as a complementary diagnostic tool in the diagnosis of severe peanut allergy in adults

Fig. 2

a OPLS column-loading plot showing the X-variables that are most strongly associated with the BAT AC50-value for peanut within the PA-group. X-variables represented by a bar pointing in the same direction as AC50 peanut (located to the far left) are positively associated, whereas variables in the opposite direction are inversely related. The OPLS plot is based on X-variables with VIP-values ≥0.88. R2Y indicates how well the variation of Y is explained, while Q2 indicates how well Y can be predicted. The univariate correlations between the variables most strongly associated with BAT AC50P in the PA-group are illustrated for: rAra h 1 (r = 0.314, p = 0.032) (b); BAT AC50 soy (r = 0.413, p = 0.04) (c); and IgE to peanut (r = 0.235, p = 0.112) (d). In the PS-group, the univariate correlations between rAra h 8 are illustrated for: BAT AC50P (r = 0.479, p = 0.024) (e); rGly m 4 (r = 0.757, p < 0.001) (f); and rBet v 1 (r = 0.676, p = 0.001) (g). PA, patients with severe peanut allergy; PS, peanut-sensitized patients

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