Table 2 Children who underwent a mixed nut challenge
From: Usefulness of open mixed nut challenges to exclude tree nut allergy in children
Case | Age (yrs) | Reason for long elimination diet | Mix | Max dose (g)* | Symptoms | Outcome | Conclusion & advice | Pre diet | Post diet | sIgE Grass | sIgE Birch | sIgE Haz | sIgE Alm | sIgE Cas | sIgE Pis | sIgE Bra | sIgE Pec | sIgE Wal |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 6,5 | Multiple sensitization and peanut allergy | A | 6,7 | Aversion with OAS, abdominal pain, vomiting | +/− | Tree nut allergy, multiple challenges | No nuts | No nuts | 0,5 | 1,5 | 13,1 | 1,1 | 3,0 | 1,2 | 0,4 | 0,6 | 0,4 |
2 | 6,6 | Multiple sensitization and reaction to 1 nut (Cas S2) | B | 13,3 | Aversion | +/− | Suspected cas/pis allergy introduction of alm, bra, pec, wal | Alm | Alm, bra, pec, wal1 | 0,2 | 0,0 | 0,9 | 0,0 | 1,1 | 0,2 | 0,0 | 0,0 | 0,0 |
3 | 15,2 | Multiple sensitization and eczema | A | 20,1 | Rhino-conjunctivitis | + | Suspected tree nut allergy, introduction of alm, bra, pec | No nuts | Alm, bra, pec1 | 10,4 | 76,0 | 21,8 | 0,3 | 1,2 | 2,1 | 0,1 | 0,3 | 7,1 |
4 | 9,7 | Multiple sensitization and peanut allergy | A | 6,7 | Rash, urticaria, conjunctivitis, sensation of throat tightness, abdominal pain | + | Tree nut allergy, multiple challenges | No nuts | Alm, wal2 | 19,6 | 37,0 | 15,5 | 2,7 | 7,9 | 7,8 | 1,5 | 0,3 | 1,2 |
5 | 9,4 | Multiple sensitization and other food allergy | A | 2,2 | OAS, rhino-conjunctivitis, vomiting | + | Tree nut allergy, multiple challenges | No nuts | No nuts | 50,0 | 101,0 | 74,0 | 0,4 | 2,7 | 4,1 | 0,2 | 0,3 | 0,3 |
6 | 5,4 | Multiple sensitization and other food allergy | A | 6,7 | Rash, rhino-conjunctivitis, angioedema, vomiting | + | Tree nut allergy, multiple challenges | Alm | Alm | 1,7 | 5,0 | 2,3 | 0,2 | 2,3 | 3,3 | 0,0 | 0,5 | 0,6 |
7 | 8 | Multiple sensitization and other food allergy | A | - | Introduction all nuts | Alm | None | 37,0 | 73,0 | 32,8 | 0,5 | 0,0 | 0,0 | 0,1 | 0,1 | 0,0 | ||
8 | 11,4 | Multiple sensitization and reaction to 1 nut (Pis S5) | B | - | Introduction tested nuts | Ntn | No nuts3 | 0,0 | 0,0 | 2,0 | 0,6 | 12,0 | 23,7 | 0,4 | 0,7 | 2,9 | ||
9 | 6,3 | Multiple sensitization and other food allergy | B | - | Introduction tested nuts | Ntn | No nuts4 | 14,1 | 101,0 | 19,7 | 0,3 | 7,3 | 10,8 | 0,0 | 0,8 | 2,8 | ||
10 | 15,4 | Multiple sensitization and peanut allergy | A | - | Introduction all nuts | Ntn | No nuts5 | 101,0 | 43,0 | 8,5 | 2,4 | 0,4 | 0,6 | 0,1 | 0,9 | 1,9 | ||
11 | 10 | Multiple sensitization and peanut allergy | A | - | Introduction all nuts | No nuts | None | 7,9 | 2,3 | 2,3 | 2,5 | 1,1 | 1,6 | 1,0 | 1,8 | 2,1 | ||
12 | 9 | Multiple sensitization and peanut allergy | A | - | Introduction all nuts | No nuts | None | 56,0 | 101,0 | 87,0 | 7,0 | 1,2 | 1,0 | 0,9 | 0,7 | 0,3 | ||
13 | 9,8 | Multiple sensitization and eczema | A | - | Introduction all nuts | No nuts | None | 11,3 | 1,4 | 0,5 | 0,3 | 0,3 | 0,6 | 0,2 | 0,2 | 0,2 | ||
14 | 9,7 | Multiple sensitization and peanut allergy | A | - | Introduction all nuts | No nuts | None | 101,0 | 101,0 | 101,0 | 7,4 | 1,6 | 2,5 | 1,2 | 2,9 | 2,6 | ||
15 | 8 | Multiple sensitization and eczema | A | - | Introduction all nuts | No nuts | No nuts6 | 19,0 | 17,8 | 8,6 | 0,3 | 0,8 | 1,0 | 0,4 | 0,0 | 0,1 | ||
16 | 17,1 | Multiple sensitization and peanut allergy | A | - | Introduction all nuts | Ntn | None | 16,0 | 36,0 | 27,9 | 2,3 | 1,8 | 1,2 | 1,1 | 0,2 | 0,4 | ||
17 | 14,1 | Multiple sensitization and other food allergy | A | - | Introduction all nuts | No nuts | None | 4,4 | 13,2 | 7,2 | 0,3 | 0,1 | 0,2 | 0,1 | 0,2 | 0,3 | ||
18 | 10 | Multiple sensitization and peanut allergy | A | - | Introduction all nuts | Ntn | None | 17,3 | 28,3 | 18.90 | 1,4 | 0,6 | 0,8 | 0,4 | 0,1 | 0,1 | ||
19 | 12,5 | Multiple sensitization and peanut allergy | B | - | Introduction tested nuts | No nuts | No nuts4 | 30,0 | 101,0 | 3.50 | 1,0 | 17,4 | 20,7 | 0,5 | 1,2 | 2,1 |