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Figure 4 | Clinical and Translational Allergy

Figure 4

From: Heterogeneous responses and cross reactivity between the major peanut allergens Ara h 1, 2,3 and 6 in a mouse model for peanut allergy

Figure 4

Mucosal mast cell degranulation after intragastric challenge with Ara h 1, 2, 3, or 6. C3H/HeOuJ mice were intragastrically exposed to PBS, (control) PE, or Ara h 1, 2, 3, or 6 and CT during a 4 week period, as described in material and methods. On day 35, mice received an i.g. challenge of PE or Ara h 1, 2, 3, or 6, depending on the protein used during sensitization, followed by blood withdrawal. Graphs depict the level of MMCP-I and histamine in plasma. Data are represented as mean ± SEM of 8 mice. *: p < 0.05 compared to control.

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