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Table 1 Threshold dosages for positive OPTs with acetylicsalicylic acid

From: Hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs): classification of a Danish patient cohort according to EAACI/ENDA guidelines

Threshold dosage (mg)

750*

667.5*

655

500*

185*

155

80*

55*

30

5

Patients n = 30

1

1

18

1

1

3

1

1

2

1

  1. Following dosages were given orally with 30-minute intervals (5 mg, 25 mg, 125 and 500 mg) adding up to a cumulative dosage of 655 mg.
  2. Mean threshold dosage: 485.3 mg.
  3. *Dosage in regime either repeated or lowered during OPT due to subjective complaints from the patient. See Methods.
  4. OPT = oral provocation test.