Figure 6

Impact of intra-nasal pre-exposition on further oral exposure to milk +/− CT. Respiratory pre-exposed mice (PBS, BLG, milk) received 6 mg of milk proteins in the presence (○) or absence (●) of CT (n = 7-8/group) according to the protocol depicted in Figure 1. Serum samples were collected at day 83 and BLG-specific IgE antibodies were quantified on individual serum samples. *p < 0.05, **p < 0.01, ***p < 0.001 using Kruskal-Wallis and Dunn’s multiple comparison posttest when compared to naive group. a indicates p < 0.05 using Kruskal-Wallis comparison between specified group.