From: Standardized food challenges are subject to variability in interpretation of clinical symptoms
Tract | Symptoms | Disagree (n =59) | Agree (n =132) | p |
---|---|---|---|---|
Upper airways | Red/itchy eyes | 10 (17) | 13 (10) | 0.168 |
Sneezing | 10 (17) | 10 (8) | 0.056 | |
Nasal congestion/rhinorrhoea | - | 10 (8) | 0.043* | |
Lower airways | Cough | 5 (9) | 6 (5) | 0.282 |
Hoarseness/difficulty swallowing | - | 3 (2) | 0.243 | |
In- and/or expiratory stridor | - | 5 (4) | 0.130 | |
Wheezing | - | 4 (3) | 0.177 | |
Dyspnoea | 3 (5) | 2 (2) | 0.153 | |
Gastro-intestinal | OAS^ | 28 (48) | 12 (9) | 0.000** |
Abdominal complaints^ | 21 (36) | 6 (5) | 0.000** | |
Vomiting | 4 (7) | 5 (4) | 0.374 | |
Diarrhoea | - | - | - | |
Skin | Contact urticaria# | 9 (15) | 13 (9) | 0.283 |
Redness | 12 (20) | 9 (7) | 0.008** | |
Pruritis | 4 (7) | 6 (5) | 0.525 | |
Urticaria | - | 10 (8) | 0.043* | |
Angioedema | - | 2 (2) | 0.342 | |
Neurological | Change in activity level/loss of consciousness | - | - | - |
Other subjective signs | Discomfort^ | 2 (3) | 10 (8) | 0.283 |
Food aversion^ | 14 (24) | 10 (8) | 0.003** | |
Number of different objective symptoms | No objective symptoms | 18 (32) | 2 (4) | Ref |
1 symptom | 22 (39) | 23 (40) | 0.005** | |
2 symptoms | 13 (23) | 22 (40) | 0.001** | |
3 symptoms | 3 (5) | 8 (15) | 0.002** |