Table 5 Sensitization (frequency and serum level) to food allergens of animal origin
From: Food allergen sensitization pattern in adults in relation to severity of atopic dermatitis
Food allergen | Total n = 211 | Mild/moderate AD n = 141 | Severe AD n = 70 | P-value n (%)1median2 | ||
|---|---|---|---|---|---|---|
Cow’s milk | n (%) | 51 (24.2) | 26 (18.4) | 25 (35.7) | 0.006* | |
nBos d 4 | n (%) | 10 (4.7) | 8 (5.7) | 2 (2.9) | n.r. | |
(α-lactalbu.) | Median (IQR) | 0.54 (0.32-2.63) | 0.54 (0.31-2.37) | 1.60 (0.40-x) | 0.60 | |
nBos d 5 | n (%) | 10 (4.7) | 6 (4.3) | 4 (5.7) | n.r. | |
(β-lactoglob.) | Median (IQR) | 1.44 (0.71-4.21) | 0.89 (0.47-3.04) | 2.59 (1.98-11.67) | 0.06 | |
nBos d 6 | n (%) | 11 (5.2) | 6 (4.3) | 5 (7.1) | n.r. | |
(serum albu.) | Median (IQR) | 1.01 (0.53-4.04) | 0.81 (0.52-5.58) | 1.54 (0.59-5.89) | 0.72 | |
nBos d 8 | n (%) | 25 (11.8) | 14 (9.9) | 11 (15.7) | 0.22 | |
(casein) | Median (IQR) | 2.23 (1.11-5.89) | 1.73 (0.80-4.75) | 3.30 (1.27-8.69) | 0.30 | |
nBos d lactoferrin | n (%) | 34 (16.1) | 16 (11.3) | 18 (25.7) | 0.008* | |
(transferrin) | Median (IQR) | 1.42 (0.68-2.45) | 0.97 (0.50-2.05) | 1.95 (1.12-2.92) | 0.05 | |
Hen’s egg | n (%) | 28 (13.3) | 16 (11.3) | 12 (17.1) | 0.24 | |
nGal d 1 | n (%) | 23 (10.9) | 12 (8.5) | 11 (15.7) | 0.11 | |
(ovomucoid) | Median (IQR) | 1.96 (0.63-5.19) | 2.84 (1.24-5.36) | 1.16 (0.46-5.19) | 0.24 | |
nGal d 2 | n (%) | 10 (4.7) | 4 (2.8) | 6 (8.6) | n.r. | |
(ovalbumin) | Median (IQR) | 1.64 (0.51-3.64) | 0.71 (0.42-4.69) | 2.21 (1.05-6.63) | 0.29 | |
nGal d 3 | n (%) | 6 (2.8) | 3 (2.1) | 3 (4.3) | n.r. | |
(ovotransfer.) | Median (IQR) | 1.08 (0.68-2.68) | 0.78 (0.69-x) | 2.04 (0.63-x) | 0.51 | |
nGal d 5 | n (%) | 4 (1.9) | 0 (0) | 4 (5.7) | n.r. | |
(serum albu.) | Median (IQR) | 0.43 (0.31-094) | - | 0.43 (0.31-094) | - | |
Fish | n (%) | 24 (11.4) | 12 (8.5) | 12 (17.1) | 0.06 | |
rCyp c 1 | n (%) | 23 (10.9) | 12 (8.5) | 11 (15.7) | 0.11 | |
(parvalb.) | Median (IQR) | 2.43 (0.50-15.0) | 2.00 (0.45-8.80) | 2.43 (0.50-21.78) | 0.30 | |
rGad c 1 | n (%) | 13 (6.2) | 5 (3.5) | 8 (11.4) | n.r. | |
(parvalb.) | Median (IQR) | 4.96 (2.47-7.85) | 5.80 (4.65-7.85) | 3.71 (0.93-18.72) | 0.24 | |
Shrimp | n (%) | 15 (7.1) | 5 (3.5) | 10 (14.3) | n.r. | |
rPen a 1 | n (%) | 8 (3.8) | 2 (1.4) | 6 (8.6) | n.r. | |
(tropomyosin) | Median (IQR) | 10.18 (1.24-33.22) | 28.44 (18.87-x) | 3.85 (0.54-37.20) | 0.18 | |
nPen i 1 | n (%) | 11 (5.2) | 4 (2.8) | 7 (10.0) | n.r. | |
(tropomyosin) | Median (IQR) | 5.33 (1.50-26.0) | 11.08 (0.91-40.31) | 5.33 (1.50-26.0) | 0.85 | |
nPen m 1 | n(%) | 13 (6.2) | 4 (2.8) | 9 (12.9) | n.r. | |
(tropomyosin) | Median (IQR) | 5.14 (0.48-30.46) | 11.24 (0.39-43.73) | 5.14 (0.70-23.89) | > 0.99 | |
Total 3 | n (%) | 75 (35.5) | 39 (27.7) | 36 (51.4) | 0.001* |