 
Cow’s milk free diet

Cow’s milk challenge†

pvalue

Controls (n = 22)


Fecal calprotectin (μg/g)

CMA positive (n = 18)

52 [33–86]*

60 [30–122]

0.5995

25 [13–50]

CMA negative (n = 39)

28 [21–36]*

33 [24–44]

0.4674

pvalue
 
*0.0203

0.0737
  
Fecal IgA (g/l)

CMA positive (n = 18)

0.54 [0.37–0.79]

0.48 [0.36–0.62]

0.4509

0.33 [0.22–0.51]

CMA negative (n = 39)

0.46 [0.35–0.61]

0.45 [0.36–0.55]

0.3138

pvalue
 
0.6349

0.8086
  
Fecal βdefensin2 (ng/ml)

CMA positive (n = 18)

38.6 [19.6–75.7]

47.50 [23.1–97.8]

0.1354

20.8 [8.6–50.0]

CMA negative (n = 39)

22.4 [14.5–34.6]

31.12 [20.5–47.3]

0.1144

pvalue
 
0.1976

0.2520
  
 Cow’s milk allergy was diagnosed with the doubleblind, placebocontrolled food challenge. Values in table are geometric means [95% Confidence Interval of the mean].
 *Mann–Whitney test pvalues reported between the two patients groups. Values below 0.05 are considered significant.
 † Fecal samples taken 3–5 days after start of cow’s milk containing challenge formula.