Figure 2

Immunogenicity and sensitising capacity of the cow’s milk proteins. The titre levels of the specific antibodies raised in rats dosed i.p. or orally with cow’s milk proteins. (A) BLG (●), ALA (■) or β-casein (▲)-specific IgG1 responses for rats immunised i.p. three times at an interval of 14 days with either BLG, ALA and β-casein, respectively, without the use of adjuvant. (B) BLG (●), ALA (■) and β-casein (▲)-specific IgG1 responses for rats dosed orally by SMP each day for seven weeks without the use of adjuvant. (C) BLG (●), ALA (■) and β-casein (▲)-specific IgE responses for rats immunised i.p. three times at an interval of 14 days with either BLG, ALA or β-casein without the use of adjuvant. (D) BLG (●), ALA (■) and β-casein (▲)-specific IgE responses for rats dosed orally by SMP each day for seven weeks without the use of adjuvant.