Skip to main content

Table 4 Overview most frequent related AEs (safety population)

From: A prospective study comparing the efficacy and safety of two sublingual birch allergen preparations

Symptom/signa

 

SUB-B

Stal-B

 

Grade

No. of symptoms

No. of subjects

% of subjects

No. of symptoms

No. of subjects

% of subjects

Local reactions

       

Pruritus/swelling of mouth, tongue or lip

I

44

24

63.2

31

22

61.1

II

1

1

2.6

0

0

0

Throat irritation

I

4

3

7.9

5

2

5.6

Ear pruritus

I

4

4

10.5

3

1

2.8

Nausea

I

3

2

5.3

0

0

0

Abdominal pain

I

3

3

7.9

1

1

2.8

Systemic reactions

       

Upper respiratory

       

 Rhinitis (e.g., sneezing, rhinorrhea, nasal pruritus, and/or nasal congestion)

I

10

5

13.2

8

6

16.7

 Cough

I

2

2

5.3

1

1

2.8

Conjunctival

       

 Conjunctival erythema, pruritus , or tearing

I

2

2

5.3

3

2

5.6

Other

       

 Headache

I

1

1

2.6

3

2

5.6

  1. aSymptom/sign designation according to WAO grading of local and systemic adverse events [1618].