Skip to main content

Table 1 Summary of definitions

From: Types of sensitization to aeroallergens: definitions, prevalences and impact on the diagnosis and treatment of allergic respiratory disease

Term Definition
Polysensitization Sensitization (as confirmed by SPTs or ssIgE assays) to two or more allergens
Paucisensitization Polysensitization (as confirmed by specific SPTs or ssIgE assays) to between two and four allergens.
Co-sensitization, IgE reactivity reactions in which multiple, unrelated sensitizations arise against structurally unrelated allergen groups.
Cross-sensitization/cross-reactivity, IgE reactivity reactions in which IgE antibodies are originally raised against one allergen and then bind to a similar protein in another allergen
Co-recognition A subset of cross-sensitization/cross-reactivity reactions in which the initial sensitizer is not known.
Polyallergy Clinically confirmed allergy (i.e. specific sensitization in SPTs or ssIgE assays and a causal relationship between symptoms and exposure to a specific allergen) to two or more allergens