Table 2 Data integration
Enzyme activity | Variant/ class | In vivo data | Computational | Innate immune responses | Adaptive immune responses | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Animal | Human | B cell | T cell | Barrier function (mg/ml) | Cilia beating (mg/ml) | Recovery | Cytokine profile (mg/ml) | Genomic profile | DC maturation | DC migration | T cell priming |
Protease | 1 | Animals | Epitope lists available | 0.01 | 0.01 | no | 0.001 | Analysis in progress | Analysis in progress | Â | Epitopes identified | ||
Guinea pig, Rat, Mouse Serological data | |||||||||||||
Overlaps and differences identified | |||||||||||||
| Â | 2 | 0.1 | 0.1 | no | 0.1 | Â | |||||||
| Â | 3 | 10 | 10 | yes | 10 | Â | Â | ||||||
Immunochemical characterization | |||||||||||||
Amylase | A | Epitope lists available | 10 | 10 | yes | Â | Â | Â | |||||
| Â | B | No effect | No effect | -- | Â | Â | Â | ||||||
Overlaps and differences identified | |||||||||||||
Humans | |||||||||||||
Clinical studies, Occupational data | |||||||||||||
Serological data | |||||||||||||
Others (Lipase) | Â | Â | Epitope lists available | No effect | No effect | -- | Â | Â | Â | ||||