| Baseline N=916 | 12 months N=734 | 24 months N=643 |
---|---|---|---|
Patients on OCS maintenance monotherapy, n (%) | 262 (28.6) | 118 (16.1) | 91 (14.2) |
Mean (SD) total daily OCS dose*, mg | 15.49 (14.01)a | 7.68 (10.94)b | 5.77 (8.89)c |
Mean (SD) reduction from baseline in total daily dose, mg | - | 7.89 (13.77)b | 9.95 (15.58)c |
Patients with alteration in total OCS dose, n (%) | Â | Â | Â |
• discontinuation | - | 77 (40.7)b | 82 (48.8)c |
• reduction | - | 31 (16.4)b | 34 (20.2)c |
• no change | - | 76 (40.2)b | 48 (28.6)c |
• increased | - | 5 (2.6)b | 4 (2.4)c |
Mean (SD) time to either reduction or discontinuation of OCS, days | - | 198.5 (114.29)d | 291.2 (210.86)e |