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Table 1 Characteristics peanut sensitized patients that underwent a DBPCFC

From: Plasma IL-25 is elevated in a subgroup of patients with clinical reactivity to peanut

No Sex Age Peanut-specific-IgE at diagnosis SPT at diagnosis Asthma# Atopic Dermatitis$ Clinical response to DBPCFC GI Resp Syst
(years)
1 M 10 4.0 <1 - + -    
2 M 15 0.43 <1 + + -    
3 M 16 <0.35 3 - - -    
4 M 14 2.0 2 - - -    
5 M 4 5.9 NP - - -    
6 F 3 0.6 3 - + -    
7 M 13 1.1 2 - + -    
8 M 4 7.3 <1 + + -    
9 M 15 0.6 2 - + -    
10 M 4 97.0 4 + + -    
11 M 8 0.8 3 - - -    
12 F 4 1.1 2 + + -    
13 M 5 >100 4.5 - + + + + +
14 M 9 2.2 1 + - + * * *
15* F 6 >100 3 - - + + + +
16* M 17 56.0 3.5 - + + - + -
17 M 6 >100 4 + - + + - -
18 F 7 1.9 4 + + + + + -
19 M 4 3.5 NP - + + + + +
20 M 9 >100 3 + - + + + +
21 M 7 55.0 3 + + + + - -
22 F 7 2.1 4 + + + + + +
23* M 11 4.0 2 - + + + - +
24 M 4 6.0 2 - + + + + -
25* F 6 4.9 2 - + + + + +
26 M 7 15.5 3 - - + + - +
27* M 5 21.0 2 + - + + + -
28 F 6 5.3 3 + + + + - -
29* M 6 2.2 NP + + + + + +
30 F 5 NP 2 - + + - + -
  1. Patient no. 1–12: non-responders to peanut challenge. Patient no. 13–30: positive responders to peanut challenge. # Asthma diagnosed according to ATS criteria.
  2. $Atopic dermatitis diagnosed according to criteria from Hanifin and Rajka. SPT, Skin Prick Test (the number represents the wheal size ratio peanut compared to histamine). DBPCFC, Double-Blind Placebo-Controlled Food Challenge. NP, Not performed. *Children with elevated plasma IL-25 as determined in Figure 1.
  3. GI: Gastrointestinal symptoms including stomach ache, nausea, vomiting and diarrhea; Resp: respiratory symptoms including rhinorrhea, stuffy nose; Syst: systemic symptoms including shortage of breath, systemic urticaria and angioedema.