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Table 2 Late local and systemic reactions per injection and per patient in each up-dosing regimen and the highest dose reached

From: Open-label parallel dose tolerability study of three subcutaneous immunotherapy regimens in house dust mite allergic patients

Regimen Total injections (n) LLR n (%) injections LLR n (%) patients SR n (%) injections SR n (%) patients Highest dose reached n (%) patients [95% CI]
Regular (n=5) 73 5 (7) 2 (40.0) 4 (5) 4 (80.0) 4 (80.0) [44.9-100]
Intermediate (n=19) 221 24 (11) 11 (57.9) 23 (10) 9 (47.4) 16 (84.2) [67.8-100]
Fast (n=15) 146 23 (16) 10 (66.7) 4 (3) 3 (20.0) 13 (86.7) [69.5-100]
Overall (n=39) 440 52 (12) 23 (59.0) 31 (7) 16 (41.0) 33 (84.6) [73.3-95.9]
  1. LLR= late local reaction (swelling > 5 cm), SR= systemic reaction (grade 1, early and late), CI=confidence interval.