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Table 1 Potential manifestations of food allergy eligible for inclusion

From: The acute and long-term management of food allergy: protocol for a rapid systematic review

Pathology

Disorder

IgE-mediated (acute-onset)

Acute urticaria/angioedema

Contact urticaria

Oral allergy syndrome (pollen-associated food allergy syndrome)

Allergic asthma/wheeze

Atopic eczema/dermatitis

Immediate gastrointestinal hypersensitivity such as vomiting and diarrhoea

Cell-mediated (delayed onset/chronic)

Food protein induced gastroenteropathy

Food protein-induced enterocolitis syndrome

Food protein-induced allergic proctocolitis

Atopic eczema/dermatitis

Allergic contact dermatitis

Heiner syndrome

Combined IgE and cell-mediated (delayed onset/chronic)

Atopic eczema/dermatitis

 

Eosinophilic esophagitis

 

Eosinophilic gastroenteritis

  1. Food allergy is complex and may manifest as other pathologies. As well as food allergy per se, studies of the following pathologies are eligible for inclusion, as long as there is suspicion of food allergy and the intervention focuses on addressing dietary or food-related issues. Coeliac disease is an important non-IgE mediated condition but as it has distinct symptoms and prognosis different from atopic conditions it will be excluded from this review.