| |
Total cells (× 106/lung)
|
Macro (%)
|
Eos (%)
|
Neutro (%)
|
Lympho (%)
|
|---|
|
Non-sen, PBS-expo
|
5.9 ± 0.9
|
79.1 ± 2.0
|
15.1 ± 1.4
|
4.0 ± 0.7
|
1.8 ± 0.3
|
|
Sen, PBS-expo
|
2.8 ± 0.8
|
57.2 ± 4.9*
|
31.1 ± 3.7*
|
7.6 ± 1.4
|
4.0 ± 0.6
|
|
Sen, single TMA-expo
|
4.3 ± 0.9
|
43.6 ± 3.9*
|
46.4 ± 3.3*#
|
6.9 ± 2.0
|
3.1 ± 0.5
|
|
Sen, repeated TMA-expo
|
6.3 ± 0.6
|
64.7 ± 3.5*
|
26.7 ± 2.4*§
|
6.0 ± 1.7
|
2.6 ± 0.3
|
- The number of cells in BAL fluid in non-sensitized, PBS-exposed, sensitized PBS-exposed sensitized single TMA-exposed and sensitized repeated TMA-exposed groups. Data are expressed as mean ± SEM, Mann-Whitney U test, n = 11-16. *p < 0.05 non-sensitized, PBS-exposed group versus sensitized groups. # p < 0.05 sensitized, PBS-exposed group versus sensitized, single TMA-exposed group. §p < 0.05 sensitized, repeated TMA-exposed versus single TMA-exposed group.
