| | Total cells (× 106/lung) | Macro (%) | Eos (%) | Neutro (%) | Lympho (%) |
|---|
Non-sen, PBS-expo | 5.9 ± 0.9 | 79.1 ± 2.0 | 15.1 ± 1.4 | 4.0 ± 0.7 | 1.8 ± 0.3 |
Sen, PBS-expo | 2.8 ± 0.8 | 57.2 ± 4.9* | 31.1 ± 3.7* | 7.6 ± 1.4 | 4.0 ± 0.6 |
Sen, single TMA-expo | 4.3 ± 0.9 | 43.6 ± 3.9* | 46.4 ± 3.3*# | 6.9 ± 2.0 | 3.1 ± 0.5 |
Sen, repeated TMA-expo | 6.3 ± 0.6 | 64.7 ± 3.5* | 26.7 ± 2.4*§ | 6.0 ± 1.7 | 2.6 ± 0.3 |
- The number of cells in BAL fluid in non-sensitized, PBS-exposed, sensitized PBS-exposed sensitized single TMA-exposed and sensitized repeated TMA-exposed groups. Data are expressed as mean ± SEM, Mann-Whitney U test, n = 11-16. *p < 0.05 non-sensitized, PBS-exposed group versus sensitized groups. # p < 0.05 sensitized, PBS-exposed group versus sensitized, single TMA-exposed group. §p < 0.05 sensitized, repeated TMA-exposed versus single TMA-exposed group.
