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Figure 6 | Clinical and Translational Allergy

Figure 6

From: Repeated allergen exposure reduce early phase airway response and leukotriene release despite upregulation of 5-lipoxygenase pathways

Figure 6

Production of cysLTs (LTC4/D4/E4), TXB2 and PGE2 in airway in vivo in sensitized guinea pigs after intratracheal instillation of allergen challenge. Repeated exposure to allergen (0.03% TMA-GPSA on five consecutive days) prior the challenge, significantly reduced the levels of cysLTs and TXB2 in BAL fluid after intratracheal instillation of allergen. Data are expressed as mean ± SEM, Mann-Whitney U test, *p < 0.05, n = 8 in each group.

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