The 11S globulin Sin a 2 from yellow mustard seeds shows IgE cross-reactivity with homologous counterparts from tree nuts and peanut

Table 1 Clinical characteristics of patients with mustard allergy sensitized to Sin a 2

Patient Nº		Sex/age (y)	Mustard Symptoms	SPT*		Other food allergies	SPT*					Tree nuts/ peanut Symptoms
Patient Nº		Sex/age (y)	Mustard Symptoms	Mustard	Sin a 2	Other food allergies	Almond	Hazelnut	Pistachio	Walnut	Peanut	Tree nuts/ peanut Symptoms
GROUP 1	1	F/51	OAS, U, AE, D	221	69	no	16	19	Neg	9	Neg	-
	2	M/50	OAS, AE, D	97	52	no	Neg	Neg	Neg	15	Neg	-
	3	M/29	OAS, U, RC, D	87	37	r, l, m	Neg	30	22	36	29	-
	4	M/36	OAS, U	137	139	r, m	20	10	20	18	17	-
	5	F/54	OAS, U, TT, A, RC, D	101	35	r, k	Neg	Neg	Neg	18	39	-
GROUP 2	6	F/30	OAS,CU,TT, D	119	46	k, n	15	Neg	Neg	9	7	OAS
	7	M/30	OAS,U, AE, TT, A, RC, D	103	50	r, n, p	Neg	Neg	14	Neg	Neg	OAS
	8	M/30	OAS, U, AE, TT, A, RC	171	83	n	21	14	11	8	17	OAS, RC, A
	9	M/30	OAS, AE, A, RC	169	22	r, k, n, p, m	21	82	35	124	38	OAS, AE, TT
	10	F/31	OAS, AE, CU, TT, A	55	25	r, k, n, p, m	23	57	40	59	64	OAS, AE, TT, RC
	11	M/6	OAS, TT (local)	73	8	k, n	Neg	56	Neg	54	Neg	AE, U

M/F, male/female; A, asthma; AE, angioedema; CU, contact urticaria; D, digestive symptoms; OAS, oral allergy syndrome; RC, rhinoconjuctivitis; U, urticaria; TT, throat tightness; k, kiwi; l, legumes; m, melon; n, nuts (including almond); p, peanut; r, rosaceae family (excluding almond); Neg, negative (< 0.100 for ELISA and wheal area < 7 mm² for SPT).
* Skin prick test: wheal area in mm².
Group 1: Tolerant to tree nuts and peanut.
Group 2: Symptoms with tree nuts and/or peanut.

ISSN: 2045-7022