From: Dysfunctional breathing phenotype in adults with asthma - incidence and risk factors
Risk factor | Subjects with DB (n = 16) | Subjects without DB (n = 75) | p value |
---|---|---|---|
Age (years; mean ± SD) | 37.88 ± 1.39 | 34.44 ± 1.39 | 0,2880 |
Female sex | 13(82.25%)* | 34(45.33%) | 0,0091 |
Obesity | 6(37.5%) | 37(49.33%) | 0,3894 |
Atopy | 9(56.25%) | 72(96%)* | <0,00001 |
Active smoker | 5(31.25%) | 12(16%) | 0,1554 |
Moderate/severe rhinitis | 13((82.25%)* | 41(54.67%) | 0,0494 |
Psychopathology | 12(75%)* | 2(2.67%) | <0,00001 |
GERD | 8(50%)* | 1(1.33%) | <0,00001 |
High blood pressure | 2(12.5%) | 6(8%) | 0,5639 |
Severe asthma | 9(56.25%)* | 15(20%) | 0,0028 |
Lack of asthma control | 13((82.25%)* | 4(5.33%) | <0,00001 |
Asthma duration > 5 years | 9(56.25%) | 25(33.33%) | 0,0854 |
Fixed airway obstruction | 1(6.25%) | 11(14.67%) | 0,3663 |
Fast FEV1 decline | 4(25%)* | 4(5.33%) | 0,0117 |
Frequent exacerbator | 15(93.75%)* | 8(10.67%) | <0,00001 |
Brittle asthma | 6(37.5%)* | 1(1.33%) | <0,00001 |
Lack of ICS | 4(25%) | 44(58.67%)* | 0,0143 |
Use of LABA as add-on | 7(43.75%) | 16(21.33%) | 0,0611 |
Use of LTRA | 7(43.75%) | 55(73.33%)* | 0,0211 |