Figure 1
From: Rhinovirus-induced basic fibroblast growth factor release mediates airway remodeling features
Rhinovirus (RV) infection induces bFGF release and mRNA expression in human bronchial epithelial cells. A, bFGF release by normal human bronchial epithelial (NHBE) cells exposed to RV1b or HeLa lysate (control); *p < .01, **p < .0001. B, bFGF release by BEAS-2B exposed to RV1b, heat-inactivated RV1b (hiRV), UV-inactivated RV1b (UVRV1b) or HeLa lysate (control); *p < .001. C, bFGF release by BEAS-2B infected by RV1b at different MOIs; * p < .01, ** p < .001. D, Time course of bFGF release on infection by RV1b. * p < .01, ** p < .001, *** p < .0001. For A, C and D, comparisons were made with cultures exposed to control medium. E, Relative abundance of bFGF mRNA in comparison to β-actin after RV1b infection of BEAS-2B; *p < .05; **p < .01. n ≥ 3 independent experiments.