Proteins found in caveolae and lipid rafts. | |
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Name | Functions |
ACTG, gamma actin | A subunit of microfilaments, one of the three major components of the cytoskeleton |
ANXA2, Annexin 2 | Belongs calcium-binding proteins, suppresses phospholipase A2 and thus inhibits inflammation. |
CALM, Calmodulin | Belongs calcium-binding proteins, regulation of nuclear transport. |
KCNA5 | Voltage-dependent potassium ion permeability, has a role in regulating the secretion of insulin |
PLEC1, Plectin | Intermediate filament binding protein |
STML2, Stomatin 2 | Colocalized at intercellular junctions and regulated gap junctions and lipid domain organization. |
Other epithelial proteins | |
Name | Functions |
CROCC, Ciliary rootlet | A cytoskeletal-like structure in ciliated cells |
DCD, Dermcidin | Displays antimicrobial activity thus limiting infection by potential pathogens, such as E.coli and S.aureus. |
ECHB | Participates in lipid metabolism. |
EPIPL, Epiplakin | A cytoskeletal linker protein, interactions between epiplakin and intermediate filaments |
GNDS, Ral/RalBP1 | Plays a role in endocytosis and vesicle sorting and migration. |
K1C18, Cytokeratin 18 | A subunit of intermediate filament, one of the three major components of the cytoskeleton |
MARCO | Scavenger receptor, a major mediator of non-opsonized E. coli phagocytosis clearance of bacteria in vivo |
MYCB2 | Mediates ubiquitination and subsequent proteasomal degradation of target proteins |
S100P | Overexpressed in epithelium in psoriasis, wound healing, skin cancer, inflammation, calcium-binding |
TBA8, Alpha-tubulin | The major constituent of microtubules, one of the three major components of the cytoskeleton. |