Skip to main content

Table 5 Associates of MDRS (univariate analysis)

From: Quantification of atopy, lung function and airway hypersensitivity in adults

  

tMDRS

Associate

 

p

Slope

R2

Atopy on SPT*

4.27×10-11

-1.43

0.07

   Mite

Positive SPT

1.05×10-9

-1.43

0.06

 

SPT-WMD

1.28×10-12

0.033

0.08

   Cat

Positive SPT

4.31×10-9

-1.55

0.06

 

SPT-WMD

3.09×10-11

-0.38

0.07

   Dog

Positive SPT

4.30×10-12

-2.32

0.08

 

SPT-WMD

3.95×10-12

-0.51

0.08

   Tree

Positive SPT

0.0001

-1.19

0.03

 

SPT-WMD

0.0001

-0.23

0.03

   Grass

Positive SPT

1.27×10-7

-1.31

0.05

 

SPT-WMD

5.80×10-8

-0.27

0.05

   Mould

Positive SPT

0.003

-1.92

0.02

 

SPT-WMD

0.002

-0.48

0.02

Atopy on sIgE #

3.14×10-14

-1.72

0.10

   Mite

Positive sIgE

1.04×10-11

-1.54

0.08

 

sIgE level

3.08×10-17

-0.39

0.12

   Cat

Positive sIgE

4.83×10-16

-2.08

0.11

 

sIgE level

4.83×10-16

-0.57

0.14

   Dog

Positive sIgE

2.55×10-21

-2.59

0.15

 

sIgE level

2.42×10-23

-0.72

0.16

   Grass

Positive sIgE

7.73×10-13

-1.61

0.09

 

sIgE level

1.44×10-13

-0.33

0.09

Gender - Female

1.07×10-7

-1.17

0.04

Age (years)

0.39

-0.04

0.001

BMI (%)

0.14

-0.03

0.004

FEV 1 % predicted

2.55×10-28

0.08

0.18

FVC % predicted

0.001

0.03

0.02

FEV 1 /FVC

1.18×10-27

15.79

0.18

Current Asthma

3.30×10 -32

-2.89

0.20

Cat ownership (current)

0.42

0.24

0.001

Dog ownership (current)

0.04

-0.61

0.007

Ln Der p 1 Exposure (μg/g)

0.77

0.02

0.0001

Ln Fel d 1 Exposure (μg/g)

0.26

0.06

0.002

Ln Can f 1 Exposure (μg/g)

0.02

-0.13

0.009

Smoking (Ever)

0.08

-0.40

0.005

Ln Smoke-Pack-Years

0.08

-0.03

0.005

  1. *At least one positive skin prick test result; #At least one positive sIgE result; SPT-WMD - Skin prick test wheal mean diameter (mm); sIgE level (kUA/l)
  2. BMI - Body mass index; MDRS - methacholine dose-response slope; SPT - skin prick tests; sIgE - serum specific IgE. Current Asthma - Physician-diagnosed asthma with asthma symptoms and/or use of asthma medication in the last 12 months[26].
  3. Note: tMDRS = 100/(MDRS+10), thus negative slope means increasing MDRS