Figure 6From: Intact skin and not stripped skin is crucial for the safety and efficacy of peanut epicutaneous immunotherapy (EPIT) in miceEffect of EPIT on intact or stripped skin on the mRNA expression of cytokines and transcription factors in esophagus mucosa. Cytokine mRNA from esophagus segments collected 24 hrs after stopping peanut diet was assayed by RT-qPCR. Results are presented as mRNA expression of naïve, Sham, or EPIT animals. The relative levels of gene expression were calculated by reference to mRNA levels of SDHA andβ-actin in each sample. (a) eotaxin, (b) IL-5, (c) IL-13, (d) T-bet, (e) GATA-3, (f) FoxP3. * p<0.05, ** p<0.01 , *** p<0.001.Back to article page